2,4-Bis(4-eth­oxy­phen­yl)-7-methyl-3-aza­bicyclo­[3.3.1]nonan-9-one

نویسندگان

  • Dong Ho Park
  • V. Ramkumar
  • P. Parthiban
چکیده

The mol-ecule of the title compound, C(25)H(31)NO(3), exists in a twin-chair conformation with an equatorial orientation of the 4-eth-oxy-phenyl groups, as observed for its ortho isomer [Parthiban, Ramkumar, Park & Jeong (2011b ▶), Acta Cryst. E67, o1475-o1476]. The methyl and 4-eth-oxy-phenyl groups are also equatorially oriented on the bicycle, as in the ortho analogue. In particular, although the cyclo-hexa-none ring deviates from an ideal chair, the piperidone ring is closer to an ideal chair, whereas in the ortho isomer both rings are significantly puckered and deviate from ideal chairs. The 4-eth-oxy-phenyl groups on both sides of the secondary amine group are oriented at an angle of 26.11 (3)° with respect to each other, but the 2-eth-oxy-phenyl groups in the ortho isomer are oriented by less than half this [12.41 (4)°]. In contrast to the absence of any significant inter-actions in the crystal packing of the ortho isomer, the title compound features N-H⋯O inter-actions, linking the mol-ecules along the b axis.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

2,4-Bis(4-eth­oxy­phen­yl)-1-methyl-3-aza­bicyclo­[3.3.1]nonan-9-one

In the title compound, C(25)H(30)NO(3), a crystallographic mirror plane bis-ects the mol-ecule. Although it is a positional isomer of 2,4-bis(4-eth-oxy-phen-yl)-7-methyl-3-aza-bicyclo-[3.3.1]non-an-9-one [C(25)H(31)NO(3), M(r) = 393.51; Park et al. (2012c ▶). Acta Cryst. E68, o779-780], its mol-ecular weight is 392.50 due to the 50:50 ratio of the methyl group at bridgehead C atoms. However, th...

متن کامل

2,4-Bis(2-eth­oxy­phen­yl)-3-aza­bicyclo­[3.3.1]nonan-9-one

The asymmetric unit of the title compound, C24H29NO3, contains two independent mol-ecules, which each exibit a twin-chair conformation with an equatorial orientation of the ortho-eth-oxy-phenyl groups but different dihedral angles [41.3 (1) and 24.1 (1)°] between the benzene rings. In the crystal, pairs of weak C-H⋯O hydrogen bonds link the two different independent mol-ecules into dimers.

متن کامل

2,4-Bis(2-bromo­phen­yl)-7-tert-pentyl-3-aza­bicyclo­[3.3.1]nonan-9-one

The title compound, C(25)H(29)Br(2)NO, is a tert-pentyl analog of 2,4-bis-(2-bromo-phen-yl)-3-aza-bicyclo-[3.3.1]nonan-9-one [Par-thiban et al. (2008 ▶). Acta Cryst. E64, o2385]. Similar to its analog, the title compound exists in a twin-chair conformation with an equatorial orientation of the 2-bromo-phenyl groups. The benzene rings are inclined to each other at a dihedral angle of 29.6 (3)°. ...

متن کامل

2,4-Bis(4-eth­oxy­phen­yl)-3-aza­bicyclo­[3.3.1]nonan-9-one

The title compound, C(24)H(29)NO(3), exists in a twin-chair conformation with an equatorial orientation of the 4-eth-oxy-phenyl groups. The benzene rings are inclined to each other at an angle of 28.0 (1)°. In the crystal, weak C-H⋯O inter-actions link mol-ecules related by translation into chains along the b axis. The crystal packing exhibits π-π inter-actions between the benzene rings of neig...

متن کامل

2,4-Bis(2-methoxy­phenyl)-3-aza­bicyclo­[3.3.1]nonan-9-one

In the crystal structure, the title compound, C(22)H(25)NO(3), exists in a twin-chair conformation with equatorial orientations of the meta-methoxy-phenyl groups on both sides of the secondary amino group. The title compound is a positional isomer of 2,4-bis-(2-methoxy-phen-yl)-3-aza-bicyclo-[3.3.1]nonan-9-one and 2,4-bis-(4-methoxy-phen-yl)-3-aza-bicyclo-[3.3.1]nonan-9-one, which both also exh...

متن کامل

2,4-Bis(4-chloro­phen­yl)-1-methyl-3-aza­bicyclo­[3.3.1]nonan-9-one

The title compound, C(21)H(21)Cl(2)NO, exists in a twin-chair conformation with an equatorial orientation of the 4-chloro-phenyl groups on both sides of the secondary amino group; the dihedral angle between the 4-chloro-phenyl rings is 36.58 (2)°. The crystal packing is stabilized by an inter-molecular N-H⋯O hydrogen bond and a weak Cl⋯Cl [3.4331 (9) Å] inter-action.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 68  شماره 

صفحات  -

تاریخ انتشار 2012